Urea

Diagram of the urea cycle, showcasing the biochemical pathway in liver cells that converts ammonia to urea for excretion. Key components include ammonia, carbon dioxide, ornithine, and enzymes like carbamoyl phosphate synthase. Urea is then transported to the kidneys and excreted in urine.
Detailed representation of the urea cycle, a critical metabolic pathway that detoxifies ammonia by converting it into urea, a waste product safely excreted by the kidneys.

Table of Contents

What is Urea?

Urea is a chemical compound with the molecular formula CO(NH₂)₂. It is a compound that contains carbon, oxygen, and nitrogen and is produced in the liver of animals, including humans, as a byproduct of metabolism. Urea is a nitrogen-containing waste product that is excreted from the body through urine.

Key Points about Urea

Chemical Formula

The chemical formula of urea is CO(NH₂)₂, indicating that it consists of one carbon (C) atom, one oxygen (O) atom, and four hydrogen (H) atoms.

Metabolic Byproduct

Urea is produced in the liver during the breakdown of proteins and amino acids. It is a major component of urine and is excreted from the body through the kidneys.

Nitrogen Elimination

One of the primary functions of urea is to eliminate excess nitrogen from the body. Nitrogen is a byproduct of protein metabolism, and urea provides a way for the body to remove and excrete excess nitrogen safely.

Solubility

Urea is highly soluble in water, and it easily dissolves in urine. Its solubility makes it an effective vehicle for transporting nitrogenous waste out of the body.

Fertilizer

Urea is also used as a nitrogen-rich component in fertilizers. It provides a source of nitrogen that plants can absorb and utilize for growth. In agriculture, urea is often applied to soil as a nitrogen fertilizer.

Medical Uses

Urea is sometimes used in certain medical and cosmetic products. In dermatology, it may be included in creams and lotions for its moisturizing properties.

Laboratory Applications

Urea is used in various laboratory procedures and experiments. It is a common reagent in biochemistry and molecular biology for applications such as protein denaturation and as a component of buffer solutions.

Amide Bond

Urea contains an amide bond (CO-NH₂), which is a functional group formed by the combination of a carbonyl group (C=O) and an amino group (NH₂).

Related Links

Excretion

Metabolism

Nitrogen Cycle

Placenta